Human growth hormone (HGH) levels peak in adolescence through early adulthood and start to rapidly decline after the age of 30. This decline is associated with an increase in body fat, loss of muscle mass, thinning of the skin, cognitive decline, and increased risk for cardiovascular disease. There are numerous published studies that demonstrate that replacing HGH levels to the optimal range reduces these symptoms and increases overall quality of life. Physicians are now using sermorelin and growth hormone releasing peptides (GHRP2 and GHRP6) to boost HGH levels in men and women as an alternative to injecting HGH which is expensive and restricted by FDA guidelines.
1. Why boost human growth hormone levels using sermorelin and GHRP2?
It is really important when examining the safety and efficacy of any treatment to understand what the science says. Peer reviewed published medical data shows declining HGH levels are associated with an increase in body fat, decline in muscle mass, and loss of bone mass. There is also data that demonstrates lowHGH levels associated with cognitive decline and increased risk of cardiovascular disease. In these studies, when patients injected HGH they gained muscle, lost fat, strengthened bone and reported an improvement in cognition and reduced cardiovascular risk. From an aesthetic perspective, HGH thickens the collagen and elastin layers of the skin and helps prevent wrinkles and thinning skin associated with aging. As a result of this data, many doctors recommend increasing HGH levels to the optimal range as a treatment to slow down the aging process. Getting proper rest, exercising regularly, and supplementing with glutamine, arginine, niacin, and CDP-choline (cytidine-5’-diphospate choline) may boost levels of HGH naturally. Here is a great article in Life Extension magazine on how to boost HGH naturally. http://www.lifeextension.com/magazine/2009/3/enhancing-growth-hormone-naturally/page-01
2. Why do doctors prefer to use sermorelin and GHRP2 to boost HGH levels?
Very few doctors prescribe human growth hormone to patients despite its benefits. There are two main reasons for this. The first is cost. HGH replacement can cost $650-$1,200 per month depending on the required dose. The second reason is that HGH replacement is FDA approved for HIV/AIDS and HGH deficiency. To prove an HGH deficiency you have to admit patients to the hospital and perform an insulin challenge test which is contraindicated for anyone over the age of 55, anyone with cardiovascular disease, or patients with a history of concussion. Some doctors will perform a glucagon challenge test in the office which is less costly and safer than an insulin challenge test. Based on these two tests, many patients will not qualify for HGH replacement and cannot get a prescription. To prescribe sermorelin and GHRP2, physicians can simply rely on the IGF-1 and IGF-BP3 test which is an uncomplicated blood test. In the medical literature, IGF-1 levels <175 are consistent with HGH deficiency. IGF-BP3 levels < 4000 further support deficiency in HGH. About 90% of the patients that come to my office over the age of 40 have IGF-1 levels less than 175. 3. How do sermorelin and GHRP2 work?
When injected subcutaneously at bedtime, sermorelin and GHRP2 stimulate the hypothalamus and pituitary glands to naturally make more human growth hormone when we sleep. HGH then signals the liver to produce IGF-1 and IGF-binding proteins which can have an affect on a cellular level. In my practice, I typically see IGF-1 levels increase to the 250-350 range depending on the patient. Sermorelin and GHRP2 are significantly cheaper than HGH and a month supply typically costs $275-$295. Both are tolerated very well and have very few side effects. The most common side effects I see in my practice is an occasional tingling and flushing sensation which lasts less than five minutes and it can also stimulate your appetite. Sermorelin and GHRP2 are best used on a continuous basis and not cycled as many people read on the internet. I often have patients report that their doctors checked levels once, demonstrated it was working, and then did not check IGF-1 levels again. The key is to continue to check levels periodically to make sure your body is still responding to it. Here is video on how to mix and inject sermorlin and GHRP2.
In summary, peer reviewed medical literature supports the notion that human growth hormone has many benefits on your physiology. It strengthens bone, improves cognition, reverses cardiovascular disease, increases muscle, reduces visceral fat, and improves patients’ quality of life overall. The least expensive and most effective method for increasing HGH levels is to inject growth hormone secretagogues. Data suggests that injecting sermorelin and GHRP2 are the most effective methods for increasing HGH levels. If you would like to schedule an appointment with Dr. Sean Breen,visit us at www.DoctorBreen.com and give us a call.